Since
1993, both the American Animal Hospital Association and
the
American College of Theriogenologists have
approved position statements supporting early age altering.
Scientific Studies:
It is a paradox that one of the oldest
and most commonly performed surgical procedures for companion animals
is one of the least studied. Very little scientific data exists to
propose the optimal age for altering the dog or cat. Prepubteral
altering is commonly performed in farm animals and laboratory animals.
The most obvious reason for altering pets between 5 and 7 months of age
is that veterinarians are comfortable performing surgery in this age
group and adverse outcomes are uncommon. The safety of surgery and
anesthesia for the pediatric patient has also been questioned, partly
due to unfamiliarity with pediatric patients and partly due to concerns
about anesthetic agents and protocols.
Other concerns about early age altering
center around perceived potential detrimental effects in the adult
animal. Such problems as stunted growth, obesity, behavioral changes
and lower urinary tract disease in cats have been voiced. A common
misconception that early altering predisposes male cats to urethral
obstruction or lower urinary tract disease dates back to a flawed and
outdated study (Engle, 1977). Over the last 10 years, however,
scientific evidence and clinical experience has been mounting that most
of these concerns are unfounded. There is very good scientific evidence
to show that lower urinary tract disorders in male cats are not related
to castration, but to a whole host of factors including diet.
Obesity
is a multifactorial problem with diet, exercise, breed, age and sexual
status all playing a role. Recent research into the dietary caloric
needs of intact, early altered, and conventionally altered cats (Root,
Johnston, Olson, 1996) shows that altered cats require fewer calories
and that obesity may be caused when food intake is not adjusted
accordingly. Male cats altered at both 7 weeks and 7 months required
28% fewer calories than intact male cats. Female cats altered at both 7
weeks and 7 months required 33% fewer calories than intact female cats.
Muscle development in the male cat is androgen-dependent. Therefore, a
decrease in muscularity will be seen in male cats no matter when they
are altered.
More Scientific
Studies:
In a University of Florida study (Stubbs
et al, 1996), researchers evaluated skeletal growth, as well as other
factors in 3 groups of cats: those altered at 7 weeks of age, those
altered at 7 months of age, and a sexually intact control population.
The distal radial physis normally closes after puberty, at about 14-20
months of age. It is suspected that gonadal steroids are necessary to
facilitate physeal cartilage maturation. In this study, delayed closure
of the distal radial growth plate was seen in cats altered at both 7
weeks and 7 months. However, this did not alter the mature radius/ulna
length so that there was no distinct difference among the 3 groups of
cats. Another study on radial physeal closure in early altered cats at
the University of Minnesota (Root et al, 1997) found that the mature
radius length was greater in cats altered at both 7 weeks and 7 months
versus intact cats. Therefore, it appears that altering at any age
prior to 7 months will delay physeal closure. Rather than causing
stunted growth, early altering may possibly be associated with normal
stature or increased stature. While an increased risk of physeal
fractures has been postulated to be a possible result of delayed
closure, to date, this has not been evaluated.
In
the University of Florida study, urethral pressure profilometry
revealed no adverse effects on urethral function in cats from early
altering. Urethral diameters were similar in the cats of all 3 groups.
The penis could be fully extruded in all neutered cats in this study.
The external genitalia of male and female cats in both age groups
remained infantile compared to the intact cats. In another study in
early-altered cats at the University of Minnesota (Root, Johnston,
Johnston, Olson, 1996), researchers found that there was no difference
among the same 3 groups of cats in urethral diameter (both
pre-prostatic and penile). The researchers also found that complete
penile extrusion was possible in all the control intact cats at 22
months of age. However, complete extrusion was possible in only 60% of
the cats altered at 7 months and in none of the cats altered at 7
weeks. The balanopreputial fold is an androgen-dependent membrane that
connects the preputial mucosa to the penile mucosa at birth. The
longterm significance of incomplete penile extrusion is unknown.
Behavioral characteristics were similar
between both groups of altered cats in the University of Florida study.
However, the sexually intact cats of the control population
demonstrated less affection toward humans and more interspecies
aggression. Altering at either age did not induce lethargy in male or
female cats. The body weight and body fat of both groups of altered
cats was similar, and was higher than for sexually intact cats.
Howe
et al (2000) followed a group of 263 cats from animal shelters for a
period of 37 months after gonadectomy surgery. Cats were allotted to
two groups based on age at gonadectomy: prepubertal (under 24 weeks
old) and traditional (over 24 weeks old). Telephone interviews were
conducted with the adoptive owners and veterinary records were also
examined in some cases where a medical or behavioral problem had
occurred. The study found that cats altered at less than 24 weeks of
age did not have increased incidences of infectious disease, behavioral
problems or illness of any kind during the 37-month follow-up period.
They also found that early altered cats were retained in the adoptive
homes at the same rate as cats altered at the traditional age.
Currently,
more pediatric spays and neuters are performed in animal shelters and
humane societies than in small animal veterinary practices. General
practitioners are more likely to be asked to perform early age altering
by breeder clients than the average pet owner. Many breeders now prefer
to sell only altered kittens as pets. In a recent informal survey of
cat breeders, about 70% of those surveyed held the opinion that access
to early altering was important to them (Little S, unpublished data,
2000). Another benefit is kittens that require elective surgery for
other reasons (i.e. hernia repair) may be early altered at the same
time.
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